Study of Toxic Effect of Crud Colicin Exracted from Escherchia Coli on Viability of Immune Cells.

Authors

R Essa
H Hussain
N. A A I Mohymen

Abstract

Crude-colicin was extracted from g.coli isolated from urinary tract

infection patients. Toxicity of various concentrations of crudt: colicin

on the viability of immune cells [phagocytic ceUs(M0,PMN) and lymphocytes] was studied. Results indicated that toxicity ciTect of crude colicin is dependent on concentration. Low concentrations (I0,

25, 50 mg/ml) didn't have toxic effects, but when there was an increase in the consternation of this extract, the viability of the immune cell s began to decrease.