Synthesis, Characterization and Biological Activity Study for Some New Metals Complexes with (3Z,3'E)-3,3'-(((2E,5E)-hexane-2,5-diylidene)bis(hydrazine-2,1-diylidene))bis(indolin-2-one)

Authors

Nuha Ayad Abd AL_Qadir Department of Chemistry, College of Education for Pure Sciences Ibn-Al-Haitham, University of Baghdad, Baghdad, Iraq.
Naser Dheyaa Shaalan Department of Chemistry, College of Education for Pure Sciences Ibn-Al-Haitham, University of Baghdad, Baghdad, Iraq.

DOI:

https://doi.org/10.30526/36.3.3071

Keywords:

antibiotic, FTIR, 1H-NMR, Mass, Schiff-species, Hexadion ,Isatin-3-hydrazone, Schiff_bases complexes, biological activity

Abstract

Our recent work displays the successful preparation of Schiff_bases that carried out between hexane-2,5-dione and 2 moles of (Z)-3-hydrazineylideneindolin-2-one forming in Schiff-bases-(L), Which in turn allowed combining with each of the next metal ions: (M²⁺) = Ni, Mn, Zn, Cu and Co forming complexes_ in high stability. The formation of resulting Schiff_ bases (L) is detected spectrally using LC_Mss which gave approximately matching results with theoretical incomes, ¹HNMR proves the founding of doublet signal of (2H) for 2NH, FTIR indicates the occurrence of two interfered imine bands and UV-VIS mean is also indecates the formation of ligand. On the other hand, complexes-based-Schiff were characterized using the same spectral means that relied Schiff-bases_(L). Those means gave satisfactory results and proved the distinguishable geometries that suggested. Finally, and according to the antibiotic feature of Schiff-bases and its metal ions we have also examined such character against (-Bacteria and +Bacteria) giving an acceptable inhibition efficiency.

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