Synthesis, Spectroscopic and Biological Studies of Some Metal Complexes with 2,3,5,6- O,O,O,O-tetraacetic acid Lascorbic acid

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J. S. Sultan A. A. Mukhlus F. H. Musa

Abstract

The reaction of L-ascorbic acid with the chloroacetic acid in presence of potassium hydroxide has been investigated.             The new product L (2,3,5,6-O,O,O,O-tetraacetic acid L-ascorbic acid) was isolated and characterized by elemental analysis(C.H),  1H, 13C-NMR. Mass spectrum and Fourier transform infrared (FT-IR). The reaction of the ligand (L) (where L = H4L), M+2 = (Co, Ni, Cu, Cd, Pb, Hg, Ca, Mg) has been investigated and was isolated and characterized by FT-IR, UV- visible, conductivity, Atomic absorption and molar ratio (Cd, Co) complexes.  Spectroscopic evidence showed that the binding of the M(II) ions are throughy the O-1 Lacton, O-2-OCH2COOH and O-6-OCH2COOH resulting in a six- coordinated metal ion, , Kf, max, for Co, Cd complexes, were estimated,  for Co, Ni, complexes were calculated too. The study of biological activity of the ligand (L) and its complexes (Cu+2, Cd+2, Ca+2) showed various activity toward staphylococcus aureu and Escherichia coli, except Ca- complex didn't show any effect.

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How to Cite
SULTAN, J. S.; MUKHLUS, A. A.; MUSA, F. H.. Synthesis, Spectroscopic and Biological Studies of Some Metal Complexes with 2,3,5,6- O,O,O,O-tetraacetic acid Lascorbic acid. Ibn AL- Haitham Journal For Pure and Applied Science, [S.l.], v. 24, n. 2, may 2017. ISSN 2521-3407. Available at: <http://jih.uobaghdad.edu.iq/index.php/j/article/view/766>. Date accessed: 18 sep. 2019.
Section
Chemistry