Synthesis of New 10-Amido phenoxazine Derivatives

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Israa T. Ibraheem
Suad M. Al-Araji


     This work includes synthesis of new phenoxazine derivatives containing N-substituted phenoxazine starting from phenoxazine (1).10-nitrosyl phenoxazine was prepared through the reaction of phenoxazine with sodium nitrite to give compound (2), which reacted with zinc in acetic acid to give 10-amino phenoxazine (3). Condensation of compound (3) with benzoyl chloride, isovaleryl chloride and 4-bromophenacyl chloride gave 10-amido phenoxazine derivatives (4-6).

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Ibraheem, I. T., & Al-Araji, S. M. (2017). Synthesis of New 10-Amido phenoxazine Derivatives. Ibn AL- Haitham Journal For Pure and Applied Sciences, 29(2), 144–154. Retrieved from