Estimation of Ceruloplasmin activity, and copper, iron levels in ·sera of nor1nal pregnants

Abstract

This  study  was undertaken  to shed light on the changes  of levels of CP

activity, Cu and  Fe in sera of .(53) normaJ non-smoker pregnant's  without complication, during  three1rimestcrs of pregnancy.

G1  inc.l_ude  (I 8) pre nants in  the 1' 1 tri nester, G2 19)  pret:,rp:all.ts  _wear

taken     m the  2"    tnmester  and  G3  (16) pregnants  m the  3rd  trunester.

/\nothe.r ('18) ·serum samples were taken from liealthy non-pregnant wqmen

age matched as control·group G4.

Results bowed a significant steady  elevation in CP .p:ctivity and  senm1

Cu  with adv.auccd trimester  of  pregnancy compand  to control. The  iron

concentrations  in   the   sera   of   pregnant   women   shqwed a  s gnilicant reduction  compared  to control   roup also  a steady  decrease in Fe 1evels with advanced trimester wa.s lound.

The  in .reasec..l activities   in  CP   as  Â·end<.lge11ous   antioxidant  duri.ng advanced'  pregnancy  could  be   acounter  ba1ance to   the   free·  radical gcneral·ion due to the increase in Co eo"ncentration \vilh advance gestation.