The Effect of Power He-Ne Laser on Growth of Dermatophyte Trichophyton mentagophytes

Abstract

This study aims to evaluate the effect of low power a semi-conductor He-Ne laser 4 mw power with 635 nm length on the growth and cell viability of dermatophyte Trichophyton mentagophytes. For this study, skin samples of 22 patents were collecting; those patients were suffering from dematophytsis caused by the dermatophytes, three isolates were diagnosed in dermatophytes group were T. mentagophytes.  Results showed that rays of semi-conductor laser with 635 nm wavelength of 4 mn power have affected the fungal growth T. mentagophytes (the ideal isolates) in sold media when exposed to laser radiation in different periods of 10-20 second duration, but the other two isolates gave negative results. The effects of He-Ne laser rays in dry weight matter, the results showed that the change of radiation’s time did not inhibit largely the fungal growth. According to the above results it showed that how He-Ne laser rays within 10-20 second radiation time are effective in medical treatment of experimental skin infection with T. mentagophytes. Furthermore results showed a synergistic effect between He-Ne laser and the antifungal clotrimazole on cells through reducing the minimum inhibitory concentration of antifungal after radation.