Synthesis, Characterization and Investigation of Industrial, Biological Applications for Complexes Containing Diazonium Salt of 4-Aminoantipyrine

Zahraa A.  Al-Witrry; Thaer S.  Mahmood; Maha T. Sultan; Lena J.  Kuwait

doi:10.30526/39.3.4342

Authors

Zahraa A. Al-Witrry Department of Chemistry, College of Education for Pure Science (Ibn Al-Haitham), University of Baghdad, Baghdad, Iraq. https://orcid.org/0000-0001-9934-5428
Thaer S. Mahmood Al-Rusafa First Directorate of Education, Ministry of Education, Baghdad, Iraq https://orcid.org/0009-0004-1266-2092
Maha T. Sultan Department of Chemistry, College of Education for Pure Science (Ibn Al-Haitham), University of Baghdad, Baghdad, Iraq https://orcid.org/0000-0001-9538-1288
Lena J. Kuwait Al-Rusafa First Directorate of Education, Ministry of Education, Baghdad, Iraq https://orcid.org/0009-0001-1972-1583

DOI:

https://doi.org/10.30526/39.3.4342

Keywords:

4-Aminoantipyrine, Azo dyes, Industrial applications, Metal complexes

Abstract

By reacting the diazonium salt of 4-aminoantipyrine with 2,4-dimethyphenol, 4-(2-hydroxy-3,5-dimethyl-phenylazo)- 1,5-dimethyl-2-phenyl-1,2-dihydropyrazol-3-one was synthesized. Elemental analysis (C.H.N.), FT-IR spectrum, UV-Vis spectroscopy, and ¹H NMR spectrum have been used to identify the ligand (L). To create complexes regarding the general formula [M(L)₂] with a molar ratio (1:2), the ligand (L) and the metal ion M(II), where M(II)= (Mn, Co, and Zn), have been synthesized in an alkaline medium. UV-Vis spectroscopy, FT-IR spectra, elemental analysis (A.A.), conductivity, melting point, and magnetic susceptibility have been used to identify the complexes. These complexes exhibited a tetrahedral geometry, and their antimicrobial activity was studied using both the ligand complexes (HL) and their complexes [M(L)₂]. This study revealed that Mn(II), Co (II), and Zn(II) complexes have an octahedral geometry, as indicated by spectral and physicochemical data. According to activity data, the metal complexes are more effective than the free ligand. Preliminary screening has found Co(II) and Mn(II) complexes to be extremely active against all three bacterial species.

Author Biographies

Zahraa A. Al-Witrry , Department of Chemistry, College of Education for Pure Science (Ibn Al-Haitham), University of Baghdad, Baghdad, Iraq.

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Thaer S. Mahmood , Al-Rusafa First Directorate of Education, Ministry of Education, Baghdad, Iraq

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Maha T. Sultan, Department of Chemistry, College of Education for Pure Science (Ibn Al-Haitham), University of Baghdad, Baghdad, Iraq

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Lena J. Kuwait, Al-Rusafa First Directorate of Education, Ministry of Education, Baghdad, Iraq

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