Evaluation the Effect of Catechins Extract Intake for Iraqi Male Patients With Cardiovascular Diseases CVD

Abstract

  Cardiovascular diseases CVD are responsible for the majority of death in many countries, the term cardiovascular disease CVD includes several diseases such as: coronary artery diseases (angina, myocardial infaraction MI, atherosclerosis) and stroke. These diseases cause elevation of TC, TG, LDL, VLDL, and MDA levels in plasma and decrease of HDL levels and PON activity in plasma, because of elevation in lipid peroxidation (LPO) activity.  Catechins is a water extract of green tea composed of: (-)epicatchin EC, ECG, EGC, EGCG, (+) catechin C and GC, these compounds play great roles against chronic diseases such as CVD. The effect of catechins extract on the preceding biochemical parameters was investigated in 40 volunteer male patients with CVD, catechins extract were given to patients three times daily for one month and all biochemical parameters were measured before and after adminstration with 250mg of catechins extract, then the results were compared with 30 volunteers healthy control.  The results indicated an elevation of HDL levels and PON activity, decrease of TC, TG, LDL, VLDL and MDA levels in plasma of male patients with CVD after administration of green tea catechins extract compared to control.