The Effect of Lead Pollution on GST, GPT Diseases ALP. Activity and its Relation to Liver

Abstract

The study of the effect of lead pollution on the activity of GST, GPT and ALP was undertaken occupational workers. The specimen of the project were divided into three groups according to their occupational periods as follows : Group A: 25 workers ,period of occupation 2yrs in Baghdad Factory Group B: 25 workers, period of occupation (2-10) yrs. in Baghdad factory. Group C: 25 workers. period of occupation10  yrs. in Baghdad Factory. Another group of 25 healthy unexposed to lead were considered as control group. The results showed an elevation in the activity of all enzymes under investigation in the blood of workers. The activity was positively correlated with the period of occupation i,e lead exposure. The elevation in GPT activity could be used as an damage , while elevated levels of GST occurs in all types of pollution indicator of liver to biological cells minimize the toxic effect erythrocytes and of pollutant.